Cleopatra II. was the daughter of Ptolemy V. Epiphanes and Cleopatra I. She was married to her brother Ptolemy VI. Philometor and two sons and two daughters were born in this marriage – later co-regent Ptolemy Eupator, Ptolemy (later Ptolemy VII Neos Philopator), Cleopatra Thea and Cleopatra III).
Cleopatra II. married Ptolemy VIII. Euergetes II. in 145 BC and their son was born after a year. She took over the rule of the land after a civil war in 132 BC (Ptolemy VIII and Cleopatra III were forced to flee to Cyprus), but her reign was especially based on the Greeks and the Jews, not the Egyptians. So Ptolemy VIII took the rule of the land back in 130 BC. Then Cleopatra took part in the "reign of three" (Ptolemy VIII, Cleopatra III and Cleopatra II) since 124 BC.
Ptolemy VIII. and Cleopatra II.